INTRODUCTION. Lipid altering agents encompass several classes of drugs that include hydroxymethylglutaryl (HMG) CoA reductase inhibitors or statins, fibric acid derivatives, bile acid sequestrants, cholesterol absorption inhibitors, and nicotinic acid. LIPITOR- atorvastatin calcium tablet, film coated Parke-Davis Div of Pfizer Inc----- Lipitor (atorvastatin) is a statin used for the treatment of elevated total cholesterol, LDL, triglycerides, and to elevate HDL cholesterol. Side effects of Lipitor include: Amlodipine and Atorvastatin Tablets official prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions, pharmacology and more. International Journal of Pharmaceutical Sciences Review and Research, , , , , ,, Journal of Research, Learn about Lipitor (Atorvastatin Calcium) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related medications. El hallazgo de las estatinas es una de las manifestaciones que mejor define la moderna farmacología. Inicialmente se definió exactamente la diana terapéutica donde se deseaba actuar: la HMG-CoA reductasa, enzima involucrada en la síntesis del colesterol. La Atorvastatina es un fármaco de la familia de las estatinas utilizado para disminuir los niveles de colesterol en sangre y en la prevención de enfermedades cardiovasculares. Atorvastatin calcium USP is a white to off-white crystalline powder that is insoluble in aqueous solutions of pH 4 and below. Atorvastatin calcium USP is Soluble to freely soluble in methanol, slightly soluble in alcohol, insoluble to very slightly soluble in distilled water, in pH 7.4 phosphate buffer, and in acetonitrile. Introduction Atorvastatin is a commonly used cholesterol lowering agent (statin) that is associated with mild, asymptomatic and self-limited serum aminotransferase elevations during therapy and rarely with clinically apparent acute liver injury.